General Cell Based Assays
Abcam Tyrosinase Activity Assay Kit (Colorimetric)
Tyrosinase Activity Assay Kit (Colorimetric)
The product is subject to the following: Abcam Restricted Use Statement
Meso Scale Discovery VPLEX GLP1 Active Kit 25 PL
The Meso Scale Discovery V-PLEX GLP-1 Active Kit is an electrochemiluminescent immunoassay for the quantitative measurement of active GLP-1 in human serum plasma and cell culture supernatants The kit contains a 96-well plate coated with a GLP-1 specific capture antibody a detection antibody conjugated to an electrochemiluminescent label calibrators controls assay diluent read buffer wash buffer and plate seals The assay has a range of 1 56 - 400 pg/mL and takes approximately 3 5 hours to complete This highly sensitive kit allows for the direct quantitation of active GLP-1 without sample pretreatment
Eurofins Discoverx KILR Detection Kit, 200 dp (96-well). (97-0001S)
The KILR Detection Kit is a detection kit intended for use with KILR cell lines or pools when running ADCC or other lysis-based assays. This kit contains exogenous EA as well as EFC substrate to allow for detection of lysis-based release of ProLabel-tagged KILR reporter protein. This kit contains all components required to assay 2 plates (96-well). For detailed product information, User manual and COA, visit www.discoverx.com/products/reagents/detection-kit-97-0001s.
STEMCELL Technologies Atazanavir, Size: 25 mg
Inhibit HIV-1 protease with atazanavir (IC50 2 - 5 nM Wood). Atazanavir an azapeptide binds to HIV-1 protease and prevents it from producing viral proteins rendering the virus non-infectious as no mature virions are made when HIV-1 protease is inhibited (Kohl et al.). Atazanavir is also a substrate and an inhibitor of cytochrome P450 isozyme 3A (CYP3A) and an inducer of P-glycoprotein (Perloff et al.).
Abcam Lipase Assay Kit II (Colorimetric)
Lipase Assay Kit II (Colorimetric)
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter Epoetin Alfa Bioassay Kit, 10pl. (93-0965Y3-00018)
The PathHunter Epoetin Alfa Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses erythropoetin or epoetin alfa-induced dimerization of EPOR receptors. This product uses EFC technology. The cell line included overexpresses EPOR target protein fused to PK alongside EPOR target protein fused to EA. Upon ligand-induced dimerization of EPOR, detectable EFC signal is produced. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Eurofins Discoverx PathHunter eXpress SREBP2 Nuclear Translocation Assay, 10pl Kit. (93-0830E3CP5L)
The PathHunter eXpress SREBP2 Nuclear Translocation Assay provides an easy-to-use cell based assay to study drug candidates affecting the cholesterol biosynthesis pathway. This kit assesses ligand (e.g. 5'-UMP) based pathway activation via detection of resulting SREBP2 nuclear translocation. This product uses EFC technology. The included cell line overexpresses ProLabel-tagged SREBP2 and nuclear localized EA. Upon pathway activation, induced nuclear translocation of SREBP2 leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eagle Biosciences Inc iLite® FGF-21 Assay Ready Cells
Von Willebrand factor (vWF) is a multimeric plasma glycoprotein that is required for normal hemostatic platelet plug formation. The mature plasma protein is composed of apparently identical subunits (Mr=260,000) which are held together by disulfide bonds.
Abcam Alpha Galactosidase Activity Assay Kit
Alpha Galactosidase Activity Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress GPR25 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0368E2ACP2M)
The PathHunter GPR25 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR25 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR25 and EA-tagged β-Arrestin-2. Activation of GPR25 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Cayman Chemical CellBased Assay Buffer Tablet
Cell-Based Assay Buffer Tablet has been formulated and tested to work with Cayman’s Assay Kits. Detailed instructions for its use are contained in the respective Cayman Assay Kit booklet.
Abcam NETosis Assay Kit
NETosis Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress TORC1 Nuclear Translocation Assay, 2pl Kit. (93-0833E3CP19M)
The PathHunter eXpress TORC1 Nuclear Translocation Assay provides an easy-to-use cell based assay to study drug candidates affecting the CRTC/CREB pathway. This kit assesses ligand (e.g. forskolin) based pathway activation via detection of resulting TORC1 (CRTC1) nuclear translocation. This product uses EFC technology. The included cell line overexpresses ProLabel-tagged TORC1 (CRTC1) and nuclear localized EA. Upon pathway activation, induced nuclear translocation of TORC1 leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.